Method structure / new protocols / software products:
- NGS and high throughput fragment analysis techniques (MLVA) for zoonotic agents PBA zoo
- DNA/ RNA isolation from rodent tissue
- Establishment of the pyrosequencing method for testing cerebrospinal fluid samples for infectiological agents in unexplained human meningitis
- Further development of Luminex technology for the detection of toxins in food and biosamples (development using the example of botulinum neurotoxin (BoNT))
- Modelling method/modelling tool to identify potential risk areas for zoonoses taking into account current climate and other research data; vulnerability analysis [Zoonosis RISKTOOL 2]
- Establishment of siRNA knock-out on primary avian macrophages to study host-pathogen interaction; protocols for isolation and transfection of macrophagesi RNA knock-down
- Simulation software for epidemic models using the example of influenza
- Modern Listeria typing for outbreak investigation
Biobanks / pathogen banks / databases
- Rodent biobank (faeces, intestine, auricle, liver, kidney, spleen, transudate, including biometric data)
- Rodent pathogen database (isolated pathogens are decentralized)
- Biobank on organs, secretions and excrements of red deer in Bavaria
- Giardia Biobank (human and animal isolates)
- Isolate bank of C. difficile, isolated from dogs, cats and humans
- Faeces samples (dog, cat, human) [Besides the samples from the project on Clostridium difficile there are also faeces and stool samples from a Giardia project].
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MALDI-TOF database for the identification of Arcobacter
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Arcobacter strain and data collection including characterization of the strains
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Standardised test material from croissants (tissue samples and swab samples)
Libraries
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Antibody library for the identification of glycolipid receptors
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Thogotovirus antigen bank as a diagnostic tool
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Human, mosquito and sheep lectin library for binding studies with viral glycoproteins
In vitro and in vivo models
- Bank vole model for the study of zoonoses in wild rodents
- Human liver cell model for the investigation of liver diseases
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Mosquito cell model for isolating arboviruses
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Respiratory and renal epithelial cell model from rodents and insectivores to study zoonoses without animal experiments
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Skin model (probably from 2017) for research into skin mycoses and parasitoses
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Squirrel animal model [ - expected from 2017 - ] Characterized squirrel cell lines
Maps and atlases
- Risk map for hantaviruses and other rodent associated zoonoses in Baden-Württemberg based on rodent and environmental data
- Risk maps to predict the prevalence of emerging zoonoses
- Model of hazard maps with spatial and temporal analysis of regions in relation to specific vectors or pathogens
- Tick Atlas (from 2017)
