Pilot project: In vitro model for experimental infection research - INVENT
The INVENT pilot project was devoted to method development with the aim of reducing the use of animal experiments. Using the example of the pathogen Francisella tularensis, which is responsible for tularaemia in humans and rabbits, a liver cell model was developed and tested. The complex liver tissue consisting of human hepatocytes, cholangiocytes, sinusoidal endothelial cells, Ito cells and...