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Establishment and evaluation of organoid cultures from the intestine of bats as a culture system for the isolation, replication and characterisation of bat viruses (Pilot project)

The aim of our project is to establish a cell culture model that enables the isolation of viruses from bats and the characterisation of their replication properties. Since genomic viral RNA has been detected very frequently in faecal samples, differentiated intestinal epithelial cells appear to be promising target cells. This cell type can be used for experimental purposes in the form of...
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Determination of prevalence and predilection sites of Trichinella spp. in raccoons (Procyon lotor) in Germany (pilot project)

An important potential source of infection with zoonotic pathogens is the consumption of game meat. This is also gaining in importance under the influence of the public discussion on livestock farming. In addition to the classic game species (roe deer, red deer, wild boar, etc.), new "unusual" game species are increasingly finding their way onto menus. For example, an increasing trend of eating...
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Zoonotic potential of rat hepatitis E virus in Germany (ZoRaHED) (pHD project)

Infections with the hepatitis E virus (HEV) can lead to acute hepatitis in humans. In transplantation patients, chronic hepatitis frequently occurs, which often leads to a life-threatening liver cirrhosis. The number of notified hepatitis E cases in Germany has been continuously increased in the last years. Here, the HEV genotype 3 (GT3) is mainly found, which is distributed in pigs and can be...
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international research project BMZ/ BMU

The German Research Platform for Zoonoses and the " International Alliance against Health Risks in Wildlife Trade " are launching a joint project call. The thematic focus is on the emergence and spread of zoonotic pathogens at the human-wildlife interface. Various research projects dealing with zoonotic pathogens can be applied for via the Zoonoses Platform. The funding includes pilot and cross...
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Event Reports

In addition to the International Symposium on Zoonoses Research, which takes place annually in Berlin, the National Research Platform for Zoonoses organizes numerous workshops on specific topics. These workshops are intended to promote interdisciplinary exchange and serve to initiate new cooperations and projects in the field of zoonoses research. The events are partly organized in cooperation...
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Promotion of Junior Scientists

Promotion of junior scientists The Zoonoses Platform supports doctoral students and postdocs (in their first years), who are active in zoonoses research, in their career planning/development and in the establishment of interdisciplinary networks. The support includes special events, active involvement of young scientists in the activities and decisions of the platform, and support of...
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Generation of cDNA libraries to identify novel host factors involved in zoonotic virus propagation

Viral and host-cell proteins establish a range of molecular interactions during infection. This virus-hostinteractome is unique for each virus and host species. Many host-cell factors are hijacked during infection and contribute to viral spread. At the same time, antiviral factors are induced which target different viral proteins and suppress virus production. This project aims to identify novel...
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RubiZoo

Rubellavirus (RuV), the causative agent of human rubella (“German measles”), which has been known for more than 200 years, was long considered the only representative of the genus Rubivirus (family Matonaviridae ). However, only recently novel rubiviruses have been identified in animals, suggesting a zoonotic origin of RuV. Rustrelavirus (RusV), first discovered in Germany, has been detected in...
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Associated projects

Investigations of the interactions of zoonotic pathogens in humans and animals (SHIP-NEXT Module One Health)